dr R K Sabharwal
Pediatric Neurologist

About Author

Acute disseminated encephalomyelitis (ADEM) is a fulminant inflammatory demyelinating syndrome, more common in children, manifesting with encephalopathy and polyfocal neurological deficits. Many children with ADEM report a prodromal illness - who typically experience three to six viral infections per year in the first six to eight years of life. No single infectious pathogen is reliably implicated in ADEM. A clear preceding infection or vaccination is not found. Systemic symptoms including fever, headache, malaise, and myalgias may occur shortly before the appearance of neurologic signs and symptoms. The most common signs include depressed consciousness; acute hemiparesis and ataxia. Depressed mental status should be present in all cases of ADEM. Meningismus, caused by inflammation in subarachnoid space, can also be found on neurologic examination. Though its mostly a monophasic disease, ADEM cases can have relapses in the future. (To Continue next day…)



Posted On: 03/05/2018

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