dr V K Khanna
Consultant Pediatrician

About Author

An inevitable complication of blood transfusions is iron overload. Assessment of iron overload by serum ferritin is widely used, relatively easy to perform and most acceptable, but ferritin fluctuates with infection and inflammation. Therefore, serial measurements and trend of serum ferritin values should be considered.


Assessment of liver iron concentration (LIC) by liver biopsy is invasive and cannot be performed repeatedly. Superconducting Quantum Interference Device (SQUID) measures LIC accurately. There are only few SQUID machines available worldwide as it is an expensive equipment to purchase and maintain.


Recently, magnetic resonance imaging (MRI) using T2* and R2* relaxation parameters has been used to quantitatively assess iron overload in liver and heart. Cardiac T2* value <20 milliseconds and liver T2* value< 6.3 milliseconds indicate iron overload.

Posted On: 07/09/2018

Did you find this post helpful?
Yes (35)
No (13)
35 People found this post helpful.

Read more related information, Click Here

If you have a question on some other topic, Click Here

top hospitals in india
To visit our website please click here
BLK Super Speciality Hospital
Pusa Road, New Delhi-110005
Disclaimer: Although every effort is made to give correct knowledge but legality of every answer can not be guaranteed. All answers are based on professional knowledge of Specialists.