IAP Advisory Committee on Vaccines & Immunization(ACVIP) endorses the use of Rabies Human Monoclonal Antibody(RHMAB) as an alternative to Rabies Immuno Globulin (RIG) – human or equine – along with rabies vaccines in all category-III bites.
RHMAB is licensed in India and is available as Rabisheild by Serum Institute of India.
Preparation available as 2.5 ml vial with 100U RHMAB per vial.
The recommended dose is 3.33 IU/kg body weight, same for children and adults. The dose should preferably be given at the time of the first vaccine dose, however, this may also be administered up to the 7th day after the first dose of vaccine is given.
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