Infantile colic is a benign self limited condition. There is no proven therapy for it.
Specific possible causes if identified (as mentioned in earlier post), should be addressed appropriately.
Parental reassurance is the main measure to manage an infant with colic.
Recent meta-analyses and one systematic review found that Lactobacillus reuteri significantly decreased colic in breast fed infants but it increases crying or fussing in formula fed infants.
So, Lactobacillus reuteri (DSM 17938) may be considered as a treatment option for exclusively breastfed infants and not in formula-fed infants, only in selected cases if parental distress persists despite of reassurance.
There is no role of semethicone, proton pump inhibitorsin infant with colic.
Dicyclomine is better than placebo but it is contraindicated in infants less than 6 months of age because of adverse effects.
Prevalence of colic is similar in breast fed and top fed infants. So breast feeding should be continued. Elimination of food allergens from maternal diet in breast fed infants with colic and role of hypoallergen formula in infantile colic is controversial.
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