Several studies have indicated that persons who have previously received complete pre or post-exposure prophylaxis will elicit an anamnestic response (rapid appearance of antibodies) to one or more booster doses of rabies vaccine even if the initial series of vaccination was administered several years previously.
Based on the above if re-exposed persons who have previously received and documented full pre- or post-exposure prophylaxis (either by IM or ID route) with a cell-culture vaccine or PDEV should now be given only two booster doses intramuscularly on days 0 and 3. Proper wound toilet should be done. Treatment with Rabies Immunolobulin (RIG)/MonoclonalAntibodyis not required.
NOTE: Anti-rabies titers can be done to access the efficacy of the vaccines, from National Centre For Disease Control, 5, Shamnath Marg, Delhi - 110 054 on request.
NCDC (NICD)- 01123909257 , 01123913148, 01123971272/060/344
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