dr Saurabh Chopra
Pediatric Neurologist

About Author

Valproate is a commonly used as well as abused anti-epileptic drug. It is a broad spectrum anti-epileptic which means that it is effective in nearly all types of seizures viz- generalized tonic, clonic, myoclonic, absences etc.It is only marginally effective in infantile spasms and should not be used as a first line in this seizure type. It can rarely cause irreversible liver toxicity in children below 2 years of age and should not be prescribed without due and clear counseling about rare risk of death. It should be avoided in teenage girls due to its teratogenic potential and also other side effects like- facial hair growth, polycystic ovarian disease , weight gain, scalp hair loss. Doses- start at 10mg /kg/ day build up to 15-20mg/kg /day in two-three divided doses.Tablets are available in 200 mg .Syrup 200mg/5ml. Children who can swallow tablets should be given extended release preparations for better compliance. Extended release tablets come in 200,300 and 500 mg to be given once or twice daily.

 



Posted On: 30/05/2018

Did you find this post helpful?
Yes (75)
No (13)
75 People found this post helpful.

Read more related information, Click Here

If you have a question on some other topic, Click Here

top hospitals in india
To visit our website please click here
Address:
BLK Super Speciality Hospital
Pusa Road, New Delhi-110005
Disclaimer: Although every effort is made to give correct knowledge but legality of every answer can not be guaranteed. All answers are based on professional knowledge of Specialists.