Infantile colic is a benign, self-limited process in which a healthy infant has paroxysms of inconsolable crying.
The standard diagnostic criteria—known as the “rule of three”—is crying more than three hours per day, more than three days per week, for longer than three weeks.
Symptoms typically resolve by three to six months of age. Colic affects 10% to 40% of infants and typically peaks at about 6 weeks of age, and is often associated with significant parental guilt, frustration and multiple pediatrician visits. The incidence is equal between sexes, and there is no correlation with type of feeding (breastfeeds vs. formula), gestational age (full term vs. preterm), socioeconomic status, or season of the year.
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