Wilson’s disease may present symptomatically at any age, although the majority presents between ages 5 and 35. Presentation can be multisystemic. Hepatic involvement can vary from asymptomatic transaminitis to fulminant hepatic failure or chronic hepatitis and cirrhosis. Coombs negative hemolytic anemia and neuropsychiatric manifestations are some of the other common manifestations. Less common manifestations include gigantism, and renal abnormalities including aminoaciduria and nephrolithiasis, hypercalciuria and nephrocalcinosis. Diagnosis is made when at least three of the following five criterias are met-
Treatment is by giving copper chelators viz. D – Penicillamine.
Read more related information, Click Here
If you have a question on some other topic, Click Here